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Natural Factors SAMe, 200 mg, 60 Tablets JOINT HEALTH making it suitable for individualsNatural Factors SAMe, 200 mg, 60 Tablets, is a dietary supplement designed to support mental and joint health. SAMe (Sadenosylmethionine) is a natural molecule formed in the body from methionine. It helps raise levels of serotonin, dopamine, and phosphatidylserine, which are important for mood regulation and brain function. SAMe also works with folic acid and vitamin B12 to promote healthy brain functioning. This supplement supports joint health by